Biodegradable microparticulate drug delivery system of diltiazem HCl
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چکیده
منابع مشابه
Biodegradable microparticulate drug delivery system of diltiazem HCl
The efficacy of a drug in a specific application requires the maintenance of appropriate drug blood level concentration during a prolonged period of time. Controlled release delivery is available for many routes of administration and offers many advantages (as microparticles and nanoparticles) over immediate release delivery. These advantages include reduced dosing frequency, better therapeutic...
متن کاملReview on Microparticulate Drug Delivery System
The controlled release of drugs in slow and sustained manner is one of the major challenges in drug delivery system. Targeting of drug to the particular site is an important aspect of drug delivery system. Microparticles were initially developed as carrier for vaccines & anticancer drugs. They have now been used to increase the efficiency of drug delivery system & improve release profile & for ...
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Purpose: To formulate and evaluate floating microparticulate oral diltiazem delivery system for possible delivery to the heart. Method: Floating microspheres were prepared using cellulose acetate and Eudragit RS100 polymers by emulsion solvent evaporation technique. The dried floating microspheres were evaluated for micromeritic properties (flow properties, density, particle size determination)...
متن کاملDesign of Gastro Retentive Drug Delivery System of Diltiazem Hydrochloride
L. K. Omray Ravishankar College of Pharmacy, Bhopal E.mail: [email protected] Abstract Gastro retentive drug delivery system of diltiazem hydrochloride was designed and evaluated for its effectiveness for the management of mild to moderate hypertension. Gastro retentive drug delivery system were prepared using polyvinyl alcohol and sodium carboxy methyl cellulose as the polymers and sodium...
متن کاملDiltiazem HCl CD Capsules
Hypertens ion: Diltiazem HCl CD produces its antihypertensive effect primarily by relaxation of vascular smooth muscle and the resultant decrease in peripheral vascular resistance. The magnitude of blood pressure reduction is related to the degree of hypertension; thus hypertensive individuals experience an antihypertensive effect, whereas there is only a modest fall in blood pressure in normot...
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ژورنال
عنوان ژورنال: Brazilian Journal of Pharmaceutical Sciences
سال: 2012
ISSN: 1984-8250
DOI: 10.1590/s1984-82502012000400014